12 Jun calcification of the aortic arch: risk factors

Adjusting for cardiovascular risk factors or ultrasound carotid plaque scores did not change these results. Progression of Aortic Arch Calcification Over 1 Year Is an Independent Predictor of Mortality in Incident Peritoneal Dialysis Patients Mi Jung Lee, Dong Ho Shin, Seung Jun Kim, Hyung Jung Oh, Dong Eun Yoo, Kwang Il Ko, Hyang Mo Koo, Chan Ho Kim, Fa Mee Doh, Jung Tak Park, Seung Hyeok Han , Tae Hyun Yoo , Kyu Hun Choi, Shin Wook Kang Iribarren C, Sidney S, Sternfeld B, Browner WS. ... calcification correlates better with MRI tissue changes than coronary or aortic arch calcification." This condition affects the aortic valve and may lead to aortic stenosis. Arterial calcification was a risk factor for stroke and dementia and was linked with vascular brain disease. Noncontrast abdominal CT scans obtained for other indications may provide an opportunity to quantify abdominal aortic calcification. 2000;283(21):2810. Progression of aortic arch calcification (AoAC) can be simply estimated with an AoAC score (AoACS) using plain chest radiography. Calcific atherosclerotic plaque at the aortic root. Iribarren C, Sidney S, Sternfeld B, Browner WS. These factors may be linked to aortic valve stenosis, so it's a good idea to keep your weight, blood pressure and cholesterol levels under control if you have aortic valve stenosis. We aimed to compare the relationships between CAC and AAC and cardiovascular disease (CVD) risk factors. As the degree of calcification increases, the risk of poor prognosis increases [8,9,10,11]. METHODS: The study was embedded in the population-based Rotterdam Study and comprises 2521 persons (mean age 69.7±6.8 years, 48% males) that underwent an MDCT scan. Risk factors of aortic valve regurgitation include: Older age; Certain heart conditions present at birth (congenital heart disease) The prevalence of coronary calcification was 81.7%; for aortic arch calcification, extracranial carotid artery calcification, and intracranial carotid artery calcification, this was 92.4, 72.8, and 81.5%, respectively. 2810 - 2815 View Record in Scopus Google Scholar It occurs due to the buildup of fats, cholesterol and other substances in and on the artery walls. The distribution of epicardial fat volume in these groups is shown in Supplementary material online, Table S1. 38, no. Calcification of the aortic arch: risk factors and association with coronary heart disease, stroke, and peripheral vascular disease. As the degree of calcification increases, the risk of poor prognosis increases [8,9,10,11]. After adjustment for other clinical and sociodemographic variables, aortic arch calcification was associated with an increased risk for coronary heart disease - a 27 percent increase for men and a 22 percent increase for women. The classified TAC and coronary risk factors were evaluated for the presence or absence of … Addressing risk factors for coronary artery disease. Iijima K, Hashimoto H, Hashimoto M, et al. Calcification of the aortic arch: risk factors and association with coronary heart disease, stroke, and peripheral vascular disease. Aortic valve sclerosis is defined as the thickening and calcification of the aortic valve without an obstruction of the ventricular flow of blood. 2000 Jun 7;283(21):2810-5. Calcification of the aortic arch: risk factors and association with coronary heart disease, stroke, and peripheral vascular disease. The thoracic aorta was divided into 4 locations according to the aortic anatomy (inner curve of the aortic arch, aortic arch but not on the inner curve, ascending aorta, and thoracic descending aorta). Some other risk factors include obesity, poor exercise habits, stress and hypertension. Calcification of the aortic arch: risk factors and association with coronary heart disease, stroke, and peripheral vascular disease. Materials and Methods . Factors associated with aortic arch calcification and its progression. In our cross-sectional study, 75 patients with RA were compared with 75 age-matched and sex-matched control participants. Those with unicuspid aortic valve typically need intervention when very young, often as a newborn. Previous reports have shown that simple assessment of aortic arch calcification (AoAC) using plain radiography is associated with cardiovascular mortality in the general population. PubMed Article CAS Google Scholar 15. CAS PubMed Article Google Scholar 27. Thoracic aortic calcification is associated with an increased risk of death and cardiovascular disease. Iijima K, Hashimoto H, Hashimoto M, et al. Chest radiography is a routine clinical examina - tion for patients with chest pain, and it can clearly detect calcification of the aortic arch. Atherosclerosis 2010;210:137–44. Age; Being Male Aortic stenosis is most commonly caused by age-related progressive calcification (>50% of cases), with a mean age of 65 to 70 years. May 8, 2019. Objectives . Background Bicuspid aortic valve (BAV) is the most common congenital cardiac malformation, which is often complicated by aortic valve stenosis (AoS). The objective of this study was to evaluate risk factors for AoAC progression. After additional adjustment for calcification in the other vessel beds, prevalent stroke was st … Studies showed that in patients with hemodialysis (HD) and PD treatment, aortic arch calcification is an independent predictor of CV mortality and all-cause mortality. The risk of the development of aortic stenosis in patients with “benign” aortic valve thickening. Advanced aortic arch calcification (AAC) detectable on chest radiograph is identified as a robust predictor of CV mortality beyond traditional risk factors of atherosclerosis (21–24). The aim of this study was to investigate the associations of carotid artery, aortic arch and coronary artery calcification as assessed by MDCT, with presence of stroke. To evaluate risk factors for aortic arch calcification and its long-term association with cardiovascular diseases in a population-based sample. The pathophysiological influence of aortic artery calcification (AAC) differs from that of coronary artery calcification (CAC). These include high blood pressure, obesity and high cholesterol levels. Read "Aortic arch calcification evaluated on chest X-ray is a strong independent predictor of cardiovascular events in chronic hemodialysis patients, Heart and Vessels" on DeepDyve, the largest online rental service for scholarly research with thousands of … Aortic arch calcification seen on chest radiograph obtained as part of a voluntary health examination was positively associated with traditional cardiovascular risk factors, including age, race/ethnicity, hypertension, and cigarette smoking, but inversely related with body mass index and family history of myocardial infarction. Associations of calcification and risk factors measured in close proximity to EBT may reflect the association of concurrent risk factors with previous levels. Methods. Calcification of the aortic arch was identified by X-ray. patients without aortic arch calcification; and (3) the relative risk of coronary disease associated with aortic arch calcification. The same factors were analyzed by logistic regression analysis and … A study led by Iijima et al. 2000;283(21):2810. Arterial calcification is one of the independent predictor factors of vascular morbidity and mortality in the elderly population . JAMA 2000; 283:2810-2815 [Google Scholar] 7. Iribarren C, Sidney S, Sternfeld B, Browner WS (2000) Calcification of the aortic arch: risk factors and association with coronary heart disease, stroke, and peripheral vascular disease. An_196225 posted: ... identified patients at risk for future myocardial infarction and coronary artery disease independent of concomitant risk factors. Lifestyle habits have a large influence on abdominal aortic calcification, notes the U.S. National Library of Medicine. Hemodial Int. S.H. independent risk factors for aortic calcification. Men who smoke, drink and have high cholesterol are more likely to develop abdominal aortic calcification and atherosclerosis. Figure 3 reveals no clear trend in the relation between severity of aortic calcification and increased risk for fracture in women (p = 0.44) or men (p = 0.29), and HRs did not statistically differ from 1.00. Symptoms and risk factors of Cardiomegaly Causes and risk factors of Constrictive Pericarditis What is coarctation of aorta and what causes it? Calcification of the aortic arch: risk factors and association with coronary heart disease, stroke, and peripheral vascular disease. Damage to the aorta near the site of the aortic valve, such as damage from injury to your chest or from a tear in the aorta, also can cause backward flow of blood through the valve. We compared the patients with brain infarcts (case patients) and the controls with respect to various vascular risk factors and the presence of aortic plaques in the ascending aorta and proximal arch. In particular, arterial calcification processes have been shown to share some pathways in common with bone physiology. The calcifications themselves are not a risk to you. JAMA. We reported the interaction between fetuin A tertile and the presence of aortic arch calcification on the risk of incident major fracture in the Table 4. S.H. Another major cause of aortic stenosis is the calcification of a congenital bicuspid aortic valve or, more rarely, congenital unicuspid aortic valve. The prevalence of coronary calcification was 81.7%; for aortic arch calcification, extracranial carotid artery calcification, and intracranial carotid artery calcification, this was 92.4, 72.8, and 81.5%, respectively. Aortic arch calcification detectable on chest X-ray is a strong independent predictor of cardiovascular events beyond traditional risk factors. Patients were followed-up for 10 years. Objective. The scale, dividing aortic arch into 16 sections by circumference, was attached to the aortic arch on chest X-rays and the number of sectors with calcification was counted. aortic artery calcification is a risk factor for adverse cardiovascular outcomes [13-15]. Studies showed that in patients with hemodialysis (HD) and PD treatment, aortic arch calcification is an independent predictor of CV mortality and all-cause mortality. Although the risk factors of repeated AVF failure particularly the factor of vascular calcification are rarely investigated, the relationship between vascular calcification and percutaneous intervention related-restenosis have been widely studied in cardiovascular diseases other than AVF [26]. Aortic valve pathology, including aortic valve calcification (AVC), has been established as an important risk factor for major cardiac events, exerting its influence independent of traditional cardiovascular risk factors or coronary artery calcification. Multivariable adjustment for risk factors resulted in attenuation of the risk estimate for cardiovascular death, which is consistent with the notion that abdominal aortic calcification (as a marker of atherosclerosis) is in the causal pathway between risk factors and fatal cardiovascular outcomes. In addition, calcification conferred a significant increase in risk for ischemic stroke among women (46 percent). This observational study found that 60% of aortic calcification is concentrated in the aortic arch and the proximal descending aorta. Analyses were performed in the first 1003 subjects. 75. Ronn, et al. The rate of progression to clinical aortic stenosis is under 2% per year. It leaves the heart and ascends, then descends back to create the arch. Common symptoms. JAMA 2000; 283:2810-2815 [Google Scholar] 8. To assess the influence of traditional cardiovascular (CV) risk factors, disease characteristics, and concomitant treatments in patients with rheumatoid arthritis (RA) on coronary artery calcification (CAC) and abdominal aorta calcification (AAC). This can cause the aorta to narrow and restrict blood flow. ... Cardiovascular risk factors were evaluated by interview, physical examination, and laboratory tests. METHODS: The study was embedded in the population-based Rotterdam Study and comprises 2521 persons (mean age 69.7±6.8 years, 48% males) that underwent an MDCT scan. The magnitude of increased relative risk, 1.2, prompted these investigators to conclude that aortic arch calcification may have prognostic value beyond the traditional risk factors … Iijima, K. et al. studied factors that are associated with the calcification of the aortic arch in patients on LTH. How bad it … Introduction. C. Iribarren, et al., “Calcification of the Aortic Arch: Risk Factors and Association with Coronary Heart Disease, Stroke, and Peripheral Vascular Disease,” JAMA 283(21), 2810–2815 (2000). Methods. Participants with the greatest severity of aortic arch calcification had a higher risk of cancer [hazard ratio for the third tertile compared to the first tertile of aortic arch calcification volume in the total population is 1.39 (95% CI = 1.04–1.86)]. [9]. Lifestyle habits have a large influence on abdominal aortic calcification, notes the U.S. National Library of Medicine. Additionally, smoking may further increase the risk of aortic arch calcification in patients with a Chinese ethic background. Subsequently, question is, what is the aortic arch? Calcification of the aortic arch was identified by X-ray. 2011;15:460-467 9. Smoking status was also risk factor in both COPD and AA, and it correlated with aortic calcification as well as the FEV 1% predicted and LAA (data not shown). : While a high coronary calcium score (CCS) is helpful (in the sense that it virtually guarantees that you have heart disease & ... Calcification of the aortic arch. Association between aortic calcification and total and cardiovascular mortality in older women. Some other risk factors include obesity, poor exercise habits, stress and hypertension. The aim of the study was to identify the factors associated with repeated arteriovenous fistula (AVF) failure within 1-year, especially the impact of aortic arch calcification (AAC) on patency of AVF. J Intern Med. Patients with chronic kidney disease (CKD) are at a high risk of end-stage renal disease (ESRD) and cardiovascular and all-cause mortality 1.Vascular calcification (VC) in … Vascular calcification and cardiomegaly are highly prevalent in chronic kidney disease (CKD) patients. Studying risk profiles in an aggregated ... aortic arch calcification (AAC), extracranial carotid ar-tery calcification (ECAC), and aortic valve calcification (AVC) were quantified using dedicated software (Syngo Age and current smoking were the strongest independent risk factors for arterial calcification. Risk factors for progression of aortic arch calcification in patients on maintenance hemodialysis and peritoneal dialysis. Ronn, et al. Aortic arch calcification detectable on chest X-ray is a strong independent predictor of cardiovascular events beyond traditional risk factors. suggested that the grading of aortic calcifications based on chest X-rays could be valuable in the management and follow-up of aortic atherosclerosis because the detected aortic arch calcifications on a plain radiograph were prominent independent risk factors for cardiovascular events . The increase in calcification was associated with age, higher levels of Ca and blood glucose. Jama. The increase in calcification was associated with age, higher levels of Ca and blood glucose. The exact cause of this is unknown but there are some common risk factors that include: aging, blunt trauma to the chest, very high blood pressure, bicuspid aortic valve, heart surgery or some other heart procedures, pregnancy, swelling of the blood vessels,etc. Aortic stenosis is thickening and tightening of the valve that leads to the heart having to work harder and the possibility of not enough blood being delivered to the body. Men who smoke, drink and have high cholesterol are more likely to develop abdominal aortic calcification and atherosclerosis. In the dialysis population, aortic calcification is associated with vascular stiffness [ 7] and peripheral arterial disease [ 8]. calcification, beyond traditional coronary risk factors, is not clearly established. [21] D.-S. Jeon, S. Atar, A. V. Brasch et al., "Association of mitral annulus calcification, aortic valve sclerosis and aortic root calcification with abnormal myocardial perfusion single photon emission tomography in subjects age [less than or equal to]65 years old," Journal of the American College of Cardiology, vol. Travis Nava. Ogawa T, Ishida H, Akamatsu M, Matsuda N, Fujiu A, Ito K, Ando Y, Nitta K. Relation of oral 1alpha-hydroxy vitamin d3 to the progression of aortic arch calcification in hemodialysis patients. Taking care of your teeth and gums. Vascular calcification is accelerated during dialysis and is known to be an important risk factor for cardiovascular disease. Aortic arch calcification detectable on chest X-ray is a strong independent predictor of cardiovascular events beyond traditional risk factors. 74. Patients were followed-up for 10 years. In patients without coronary calcifications, future cardiovascular events could be excluded. Aortic sclerosis is increasingly prevalent in older adults, as risk increases as a … 1 At the clinical level, osteoporosis and low BMD have been linked to a small increase in cardiovascular disease (CVD) risk in older populations, potentially related to vascular calcification. Risk factors. Seeing calcification in the aorta most likely means there is some atherosclerosis in your largest artery. We retrospectively assessed chest radiography in hemodialysis patients who had undergone initial AVF. Common symptoms reported by people with abdominal aortic calcification. Higher intake of α -tocopherol (105.5mg/d vs 76.4mg/d) and β-cryptoxanthin may increase risk of CV calcification while high intake of retinol (≥3000mcg/d) may increase hip fracture risk, although possibly only with vitamin D intake ≤440IU/d; the carotenoids lycopene and β-carotene, however, appear beneficial in bone. 2810 - 2815 View Record in Scopus Google Scholar To assess the influence of traditional cardiovascular (CV) risk factors, disease characteristics, and concomitant treatments in patients with rheumatoid arthritis (RA) on coronary artery calcification (CAC) and abdominal aorta calcification (AAC). K. Iijima , H. Hashimoto , +6 authors Y. Ouchi Medicine However, the association of the combination of aortic arch calcification … The results of the comparisons of patients with and without aortic arch calcification detected on chest x-ray in 3 different age groups were as follows. Aortic valve and root calcifications. Objective. CONTEXT Calcium deposits in coronary and extracoronary arterial beds may indicate the extent of atherosclerosis. AU Iribarren C, Sidney S, Sternfeld B, Browner WS SO JAMA. C. Iribarren, et al., “Calcification of the Aortic Arch: Risk Factors and Association with Coronary Heart Disease, Stroke, and Peripheral Vascular Disease,” JAMA 283(21), 2810–2815 (2000). Calcification of the aortic arch: risk factors and association with coronary heart disease, stroke, and peripheral vascular disease Jama , 283 ( 2000 ) , pp. JAMA 2000; 283:2810-2815 [Google Scholar] 8. The aortic arch calcification (AAC) extent in four-point scale and distribution of AAC grades on a chest X -ray. Arch Intern Med ... atherosclerotic risk factors on aortic valve calcification. The risk of aortic sclerosis progressing to aortic stenosis is low. The distribution of epicardial fat volume in these groups is shown in Supplementary material online, Table S1. Calcification of the aortic arch: risk factors and association with coronary heart disease, stroke, and peripheral vascular disease. AU Iribarren C, Sidney S, Sternfeld B, Browner WS SO JAMA. Need risk factors. Coronary artery calcification reflects the total plaque burden, 1 is associated with cardiovascular risk factors, 2–5 and is an independent risk factor for future ischemic cardiac and cerebral events. In this population-based study, we found a strong and graded association of prevalent stroke with carotid artery, aortic arch and coronary artery calcification, independent of cardiovascular risk factors. Furthermore, carotid artery plaque or aortic arch calcification was not associated with CV events. Secondary a priori end points were as follows: (1) calculation of the rate of severe coronary disease in patients with aortic arch calcification of 1 … In age‐ and multivariable‐adjusted analyses, aortic calcification was not associated with risk of hip fracture. In tricuspid aortic … In age‐ and multivariable‐adjusted analyses, aortic calcification was not associated with risk of hip fracture. A calcification score of 2 and above was regarded as presence of calcification while a calcification score of 0 and 1 was regarded as absence of calcification. We compared the clinical and biochemical profiles between patients with and without AAC. Non-traditional CV risk factors, e.g., calcium-phosphorus product, serum albumin and C-reactive protein, were also not found to be risk factors. Analyses were performed in the first 1003 subjects. In the final model (R2=0.44), age, systolic and diastolic BP, and serum calcium, and Lp(a) levels were independent risk factors for aortic calcification (Table 2). Oei et al.7) measured the calcification Weightlifting poses death risk Diagnosed with endocarditis and an abscess on aorta Aortic arch interruption in infants, can surgery be avoided? Figure 3 reveals no clear trend in the relation between severity of aortic calcification and increased risk for fracture in women (p = 0.44) or men (p = 0.29), and HRs did not statistically differ from 1.00. Such calcifications are often seen in people as they get older. The aim of this study was to investigate the associations of carotid artery, aortic arch and coronary artery calcification as assessed by MDCT, with presence of stroke. 2007; 261:238–244. 7, pp. Age and current smoking were the strongest independent risk factors for arterial calcification. CONTEXT Calcium deposits in coronary and extracoronary arterial beds may indicate the extent of atherosclerosis. The odds ratio (OR) for age in women, irrespective of the vessel bed, was 1.1 (P<0.001) and in men it was 1.2 with aortic arch and 1.1 with carotid calcification (both P<0.001). JAMA 283:2810–2815. E121 Patients ≤50 Years OldThe mean age of patients with aortic arch calcification was 46 ± 5, while that of patients without the calcification was 44 … Aims: Calcification in the coronary and aortic arteries has been linked to cardiovascular morbidity and mortality. Atherosclerosis 210, 137–144 (2010). JAMA 2000; 283:2810-2815 [Google Scholar] 7. Iribarren C, Sidney S, Sternfeld B, et al. Risk factors for aortic calcification in the dialysis population include calcium–phosphorus product, age, dialysis vintage, blood pressure, smoking and diabetes mellitus [ 6]. Atherosclerotic calcification is another name for atherosclerosis. Abdominal aortic calcification occurs when calcium crystals are deposited in the abdominal aorta. Calcification of the aortic arch: risk factors and association with coronary heart disease, stroke, and peripheral vascular disease.

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